Saigon Railway Station is a railway station in District 3, Ho Chi Minh City, Vietnam. This station is the largest and most important railroad transportation hub of Vietnam as Ho Chi Minh City is the largest city and the economic center of Vietnam. The station was constructed in early 1930s by the French colonists, as part of Hanoi-Saigon Railway. The station is situated around 1 km from the downtown.

Due to the requirement of urban planning, the city government is considering the relocation to the city outskirt of this station in Binh Trieu (Binh Trieu Railway Station). Every year, 1-2 months before Tet, there are always thousands of people queuing here all day to buy tickets home as this is the only booking office of Vietnam Railway Station Corporation. Though electronic booking machines have been adopted but these queue's continue due to the monopoly.

Despite the city being named Ho Chi Minh City after the war, the name of the station has remained the same as ever.